May 29, 2025
Innovation Fund Spotlight: State-of-the-Art Genome Editing To Understand Disease and Develop New Therapies
Read ArticleBlog Posts focused on: Lab Ziegler
October 4, 2024
Kazushige Ninomiya, PhD: Finding New Answers in Cancer
Read about the questions Dr. Ninomiya will ask about one of the most devastating forms of cancer.
September 28, 2023
Meet BRI's Summer 2023 Interns
Each summer, BRI hosts undergraduate interns from universities across the country. They join various BRI labs and departments to take on research projects with mentorship from our scientists. Meet this year's interns and learn about the exciting projects they worked on.
March 29, 2023
Learning How Tregs Keep Your Immune System in Check
The immune system keeps us healthy by maintaining a delicate balance. Every cell has a purpose: Some sound the alarm when they see an invader. Some attack germs that don’t belong. And some patrol the other cells in the immune system to make sure they’re doing their job.
September 15, 2022
Paving the Way for New Colon Cancer Treatments
Steven Ziegler, PhD, still has questions about a protein called thymic stromal lymphopoietin (TSLP) — even after studying it for more than 30 years. The Ziegler Lab helped establish that TSLP plays a role in asthma, lupus and several cancers.
January 17, 2022
Using Your Own Cells to Fight Autoimmune Disease
For nearly 20 years, Dr. Buckner has been working to find a more targeted approach with fewer side effects. And she’s among a handful of scientists pursuing an intriguing idea: Can we use gene editing to change cells that cause disease into cells that protect you from disease?
September 23, 2021
TSLP: From Intriguing Protein to Groundbreaking Therapy
It’s the 1990s in Seattle. Grunge music is getting national play. Amazon operates out of a garage. And a mysterious protein catches the eye of Steve Ziegler, PhD.
June 15, 2021
Understanding EOE: New Studies Shed Light on Complex Condition
Eosinophilic esophagitis (EOE), a rare immune system condition that’s connected to food allergies and causes serious inflammation in the esophagus. A BRI research team, led by Karen Cerosaletti, PhD, and Steven Ziegler, PhD, launched a study asking some key questions about EOE.
December 21, 2020
Volunteering in a COVID-19 Vaccine Trial: BRI Team Members Share Their Experience
Without clinical research participants, we might not have groundbreaking cancer treatments like immunotherapy or vaccines for polio, rubella and other life-threatening diseases.
July 10, 2020
BRI Races to Understand COVID-19
BRI scientists were sure of one thing when the novel coronavirus struck: They had the expertise to make swift progress toward understanding it and finding better treatments. “Studying how the immune system responds to viruses has been part of our work for years,” says BRI’s President Jane Buckner
September 11, 2018
Pinpointing the Connection Between Cancer and Autoimmune Disease
It might seem unlikely for scientists at Benaroya Research Institute at Virginia Mason (BRI), a research institute focused on causes and cures for autoimmune disease, to study cancer. Scientists like Dr.
