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Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.
American Journal of Physiology. Cell PhysiologyHull RL, Zraika S, Udayasankar J, Kisilevsky R, Szarek WA, Wight TN, Kahn SE -
Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.
AtherosclerosisGoueffic Y, Potter-Perigo S, Chan CK, Johnson PY, Braun K, Evanko SP, Wight TN -
Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice.
AtherosclerosisChira EC, McMillen TS, Wang S, Haw A 3rd, O'Brien KD, Wight TN, Chait A -
Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion.
DiabetesHan CY, Subramanian S, Chan CK, Omer M, Chiba T, Wight TN, Chait A -
Cutting edge: high molecular weight hyaluronan promotes the suppressive effects of CD4+CD25+ regulatory T cells.
Journal of ImmunologyBollyky PL, Lord JD, Masewicz SA, Evanko SP, Buckner JH, Wight TN, Nepom GT -
Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells.
Journal of Cellular BiochemistryLemire JM, Chan CK, Bressler S, Miller J, LeBaron RG, Wight TN -
Decorin synthesized by arterial smooth muscle cells is retained in fibrin gels and modulates fibrin contraction.
Journal of Cellular BiochemistryJohnson PY, Potter-Perigo S, Gooden MD, Vernon RB, Wight TN -
Early human atherosclerosis: accumulation of lipid and proteoglycans in intimal thickenings followed by macrophage infiltration.
Arteriosclerosis, Thrombosis, and Vascular BiologyNakashima Y, Fujii H, Sumiyoshi S, Wight TN, Sueishi K -
Glucosamine supplementation accelerates early but not late atherosclerosis in LDL receptor-deficient mice.
The Journal of NutritionTannock LR, Kirk EA, King VL, LeBoeuf R, Wight TN, Chait A -
Versican-thrombospondin-1 binding in vitro and colocalization in microfibrils induced by inflammation on vascular smooth muscle cells.
Journal of Cell ScienceKuznetsova SA, Issa P, Perruccio EM, Zeng B, Sipes JM, Ward Y, Seyfried NT, Fielder HL, Day AJ, Wight TN, Roberts DD -
Matricellular hevin regulates decorin production and collagen assembly.
The Journal of Biological ChemistrySullivan MM, Barker TH, Funk SE, Karchin A, Seo NS, Höök M, Sanders J, Starcher B, Wight TN, Puolakkainen P, Sage EH -
V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis.
Laboratory Investigation; a Journal of Technical Methods and PathologyMiquel-Serra L, Serra M, Hernández D, Domenzain C, Docampo MJ, Rabanal RM, de Torres I, Wight TN, Fabra A, Bassols A -
The vascular endothelial growth factor VEGF165 induces perlecan synthesis via VEGF receptor-2 in cultured human brain microvascular endothelial cells.
Biochimica et Biophysica ActaKaji T, Yamamoto C, Oh-i M, Fujiwara Y, Yamazaki Y, Morita T, Plaas AH, Wight TN -
Versican degradation and vascular disease.
Trends in Cardiovascular MedicineKenagy RD, Plaas AH, Wight TN -
A role for decorin in cutaneous wound healing and angiogenesis.
Wound Repair and RegenerationJärveläinen H, Puolakkainen P, Pakkanen S, Brown EL, Höök M, Iozzo RV, Sage EH, Wight TN
