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The accumulation of versican in the nodules of benign prostatic hyperplasia.
The ProstateTrue LD, Hawley S, Norwood TH, Braun KR, Evanko SP, Chan CK, LeBaron RC, Wight TN -
Hyaluronan accumulation is elevated in cultures of low density lipoprotein receptor-deficient cells and is altered by manipulation of cell cholesterol content.
The Journal of Biological ChemistrySakr SW, Potter-Perigo S, Kinsella MG, Johnson PY, Braun KR, Goueffic Y, Rosenfeld ME, Wight TN -
Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury.
The American Journal of PathologyHwang JY, Johnson PY, Braun KR, Hinek A, Fischer JW, O'Brien KD, Starcher B, Clowes AW, Merrilees MJ, Wight TN -
Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican.
Arteriosclerosis, Thrombosis, and Vascular BiologySeidelmann SB, Kuo C, Pleskac N, Molina J, Sayers S, Li R, Zhou J, Johnson P, Braun K, Chan C, Teupser D, Breslow JL, Wight TN, Tall AR, Welch CL -
Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.
Circulation ResearchTran-Lundmark K, Tran PK, Paulsson-Berne G, Fridén V, Soininen R, Tryggvason K, Wight TN, Kinsella MG, Borén J, Hedin U -
Early atherosclerosis in humans: role of diffuse intimal thickening and extracellular matrix proteoglycans.
Cardiovascular ResearchNakashima Y, Wight TN, Sueishi K -
Endogenous overexpression of hyaluronan synthases within dynamically cultured collagen gels: Implications for vascular and valvular disease.
BiomaterialsAllison DD, Wight TN, Ripp NJ, Braun KR, Grande-Allen KJ -
The effect of PPAR ligands to modulate glucose metabolism alters the incorporation of metabolic precursors into proteoglycans synthesized by human vascular smooth muscle cells.
Archives of Physiology and BiochemistryNigro J, Potter-Perigo S, Ivey ME, de Dios ST, Evanko SP, Wight TN, Little PJ -
Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease.
Respiratory ResearchMerrilees MJ, Ching PS, Beaumont B, Hinek A, Wight TN, Black PN -
Lung lining fluid glutathione attenuates IL-13-induced asthma.
American Journal of Respiratory Cell and Molecular BiologyLowry MH, McAllister BP, Jean JC, Brown LA, Hughey RP, Cruikshank WW, Amar S, Lucey EC, Braun K, Johnson P, Wight TN, Joyce-Brady M -
Arterial remodeling in vascular disease: a key role for hyaluronan and versican.
Frontiers in BioscienceWight TN -
Perlecan: a major IL-2-binding proteoglycan in murine spleen.
Immunology and Cell BiologyMiller JD, Stevens ET, Smith DR, Wight TN, Wrenshall LE -
The effect of endogenous overexpression of hyaluronan synthases on material, morphological, and biochemical properties of uncrosslinked collagen biomaterials.
BiomaterialsAllison DD, Vasco N, Braun KR, Wight TN, Grande-Allen KJ -
Hyaluronan-dependent pericellular matrix.
Advanced Drug Delivery ReviewsEvanko SP, Tammi MI, Tammi RH, Wight TN -
Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis.
The Journal of Histochemistry and CytochemistryMcDonald TO, Gerrity RG, Jen C, Chen HJ, Wark K, Wight TN, Chait A, O'Brien KD