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May 2013
Immunological biomarkers: catalysts for translational advances in autoimmune diabetes.
Clin Exp ImmunolAhmed ST, Akirav E, Bradshaw E, Buckner JH, McKinney E, Quintana FJ, Waldron-Lynch F, Nepom GT -
May 2013
A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models.
J Clin InvestDai X, James RG, Habib T, Singh S, Jackson S, Khim S, Moon RT, Liggitt D, Wolf-Yadlin A, Buckner JH, Rawlings DJ -
Jan 2013
In active relapsing-remitting multiple sclerosis, effector T cell resistance to adaptive T(regs) involves IL-6-mediated signaling.
Sci Transl MedSchneider A, Long SA, Cerosaletti K, Ni CT, Samuels P, Kita M, Buckner JH -
Nov 2012
Identification of novel HLA class II target epitopes for generation of donor-specific T regulatory cells.
Clin ImmunolStone B, Rieck M, Rawlings CA, Kas A, Shendure J, Jones H, Buckner JH -
Nov 2012
Porphyromonas gingivalis and disease-related autoantibodies in individuals at increased risk of rheumatoid arthritis.
Arthritis RheumMikuls TR, Thiele GM, Deane KD, Payne JB, O'Dell JR, Yu F, Sayles H, Weisman MH, Gregersen PK, Buckner JH, Keating RM, Derber LA, Robinson WH, Holers VM, Norris JM -
Oct 2012
A functional framework for interpretation of genetic associations in T1D.
Curr Opin ImmunolNepom GT, Buckner JH -
Sep 2012
Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
DiabetesLong SA, Rieck M, Sanda S, Bollyky JB, Samuels PL, Goland R, Ahmann A, Rabinovitch A, Aggarwal S, Phippard D, Turka LA, Ehlers MR, Bianchine PJ, Boyle KD, Adah SA, Bluestone JA, Buckner JH, Greenbaum CJ, Diabetes TrialNet and the Immune Tolerance Network. -
Aug 2012
Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis.
Arthritis RheumSnir O, Bäcklund J, Boström J, Andersson I, Kihlberg J, Buckner JH, Klareskog L, Holmdahl R, Malmström V -
Jan 2012
Altered B cell homeostasis is associated with type I diabetes and carriers of the PTPN22 allelic variant.
J ImmunolHabib T, Funk A, Rieck M, Brahmandam A, Dai X, Panigrahi AK, Luning Prak ET, Meyer-Bahlburg A, Sanda S, Greenbaum CJ, Rawlings DJ, Buckner JH -
Jan 2012
Protein tyrosine phosphatases and type 1 diabetes: genetic and functional implications of PTPN2 and PTPN22.
Rev Diabet StudCerosaletti K, Buckner JH -
Oct 2011
Low-dose antigen promotes induction of FOXP3 in human CD4+ T cells.
J ImmunolLong SA, Rieck M, Tatum M, Bollyky PL, Wu RP, Muller I, Ho JC, Shilling HG, Buckner JH -
Oct 2011
Identification and functional characterization of T cells reactive to citrullinated vimentin in HLA-DRB1*0401-positive humanized mice and rheumatoid arthritis patients.
Arthritis RheumSnir O, Rieck M, Gebe JA, Yue BB, Rawlings CA, Nepom G, Malmström V, Buckner JH -
Sep 2011
CD4+FOXP3+ T regulatory cells in human autoimmunity: more than a numbers game.
J ImmunolLong SA, Buckner JH -
Sep 2011
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.
J Clin InvestMenard L, Saadoun D, Isnardi I, Ng YS, Meyers G, Massad C, Price C, Abraham C, Motaghedi R, Buckner JH, Gregersen PK, Meffre E -
Mar 2011
An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.
Genes ImmunLong SA, Cerosaletti K, Wan JY, Ho JC, Tatum M, Wei S, Shilling HG, Buckner JH