-
Stacking the Deck: Studies of Patients with Multiple Autoimmune Diseases Propelled Our Understanding of Type 1 Diabetes as an Autoimmune Disease.
Journal of ImmunologyBuckner JH, Greenbaum CJ -
S1P1 deletion differentially affects TH17 and Regulatory T cells.
Scientific ReportsEken A, Duhen R, Singh AK, Fry M, Buckner JH, Kita M, Bettelli E, Oukka M -
The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Journal of ImmunologyMetzler G, Dai X, Thouvenel CD, Khim S, Habib T, Buckner JH, Rawlings DJ -
A novel and rapid method to quantify Treg mediated suppression of CD4 T cells.
Journal of Immunological MethodsLong AE, Tatum M, Mikacenic C, Buckner JH -
Impact of Age and Antibody Type on Progression From Single to Multiple Autoantibodies in Type 1 Diabetes Relatives.
The Journal of Clinical Endocrinology and MetabolismBosi E, Boulware DC, Becker DJ, Buckner JH, Geyer S, Gottlieb PA, Henderson C, Kinderman A, Sosenko JM, Steck AK, Bingley PJ, Type 1 Diabetes TrialNet Study Group. -
The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.
Nature ImmunologyGorman JA, Hundhausen C, Errett JS, Stone AE, Allenspach EJ, Ge Y, Arkatkar T, Clough C, Dai X, Khim S, Pestal K, Liggitt D, Cerosaletti K, Stetson DB, James RG, Oukka M, Concannon P, Gale M Jr, Buckner JH, Rawlings DJ -
Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.
Science ImmunologyCarmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James EA, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ -
Omega-3 fatty acids are associated with a lower prevalence of autoantibodies in shared epitope-positive subjects at risk for rheumatoid arthritis.
Annals of the Rheumatic DiseasesGan RW, Demoruelle MK, Deane KD, Weisman MH, Buckner JH, Gregersen PK, Mikuls TR, O'Dell JR, Keating RM, Fingerlin TE, Zerbe GO, Clare-Salzler MJ, Holers VM, Norris JM -
The BANK1 SLE-risk variants are associated with alterations in peripheral B cell signaling and development in humans.
Clinical ImmunologyDam EM, Habib T, Chen J, Funk A, Glukhova V, Davis-Pickett M, Wei S, James R, Buckner JH, Cerosaletti K -
Editorial overview: Autoimmunity.
Current Opinion in ImmunologyHaskins K, Buckner JH -
Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.
Front ImmunolGerstner C, Dubnovitsky A, Sandin C, Kozhukh G, Uchtenhagen H, James EA, Rönnelid J, Ytterberg AJ, Pieper J, Reed E, Tandre K, Rieck M, Zubarev RA, Rönnblom L, Sandalova T, Buckner JH, Achour A, Malmström V -
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.
Science Translational MedicineHundhausen C, Roth A, Whalen E, Chen J, Schneider A, Long SA, Wei S, Rawlings R, Kinsman M, Evanko SP, Wight TN, Greenbaum CJ, Cerosaletti K, Buckner JH -
Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining.
Nature CommunicationsUchtenhagen H, Rims C, Blahnik G, Chow IT, Kwok WW, Buckner JH, James EA -
Distinct T cell signatures define subsets of patients with multiple sclerosis.
Neurology Neuroimmunology & NeuroinflammationJohnson MC, Pierson ER, Spieker AJ, Nielsen AS, Posso S, Kita M, Buckner JH, Goverman JM -
Associations of Smoking and Age With Inflammatory Joint Signs Among Unaffected First-Degree Relatives of Rheumatoid Arthritis Patients: Results From Studies of the Etiology of Rheumatoid Arthritis.
Arthritis & RheumatologySparks JA, Chang SC, Deane KD, Gan RW, Kristen Demoruelle M, Feser ML, Moss L, Buckner JH, Keating RM, Costenbader KH, Gregersen PK, Weisman MH, Mikuls TR, O'Dell JR, Holers VM, Norris JM, Karlson EW
