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Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
The Journal of Allergy and Clinical ImmunologyReeves SR, Kolstad T, Lien TY, Elliott M, Ziegler SF, Wight TN, Debley JS -
Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis.
DiabetesBogdani M, Johnson PY, Potter-Perigo S, Nagy N, Day AJ, Bollyky PL, Wight TN -
Versican and the regulation of cell phenotype in disease.
Biochimica et Biophysica ActaWight TN, Kinsella MG, Evanko SP, Potter-Perigo S, Merrilees MJ -
Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion.
The Journal of Biological ChemistryKang I, Yoon DW, Braun KR, Wight TN -
Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation.
Immunologic ResearchRuppert SM, Hawn TR, Arrigoni A, Wight TN, Bollyky PL -
Versican and the control of inflammation.
Matrix BiologyWight TN, Kang I, Merrilees MJ -
A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease.
Matrix BiologyChang MY, Tanino Y, Vidova V, Kinsella MG, Chan CK, Johnson PY, Wight TN, Frevert CW -
ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro.
The Journal of Histochemistry and CytochemistryObika M, Vernon RB, Gooden MD, Braun KR, Chan CK, Wight TN -
Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells.
The Journal of Biological ChemistryViola M, Bartolini B, Vigetti D, Karousou E, Moretto P, Deleonibus S, Sawamura T, Wight TN, Hascall VC, De Luca G, Passi A -
Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.
Mechanisms of DevelopmentWilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW -
miRNAs regulate expression and function of extracellular matrix molecules.
Matrix BiologyRutnam ZJ, Wight TN, Yang BB -
Sputum hyaluronan and versican in severe eosinophilic asthma.
International Archives of Allergy and ImmunologyAyars AG, Altman LC, Potter-Perigo S, Radford K, Wight TN, Nair P -
Cleavage of hyaluronan is impaired in aged dermal wounds.
Matrix BiologyReed MJ, Damodarasamy M, Chan CK, Johnson MN, Wight TN, Vernon RB -
Overall sulfation of heparan sulfate from pancreatic islet β-TC3 cells increases maximal fibril formation but does not determine binding to the amyloidogenic peptide islet amyloid polypeptide.
The Journal of Biological ChemistryHull RL, Peters MJ, Perigo SP, Chan CK, Wight TN, Kinsella MG -
The role of hyaluronan and the extracellular matrix in islet inflammation and immune regulation.
Current Diabetes ReportsBollyky PL, Bogdani M, Bollyky JB, Hull RL, Wight TN