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Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo.
Matrix BiologyKeire PA, Bressler SL, Mulvihill ER, Starcher BC, Kang I, Wight TN -
Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization.
PNAS USAKuipers HF, Rieck M, Gurevich I, Nagy N, Butte MJ, Negrin RS, Wight TN, Steinman L, Bollyky PL -
Serum amyloid A impairs the antiinflammatory properties of HDL.
The Journal of Clinical InvestigationHan CY, Tang C, Guevara ME, Wei H, Wietecha T, Shao B, Subramanian S, Omer M, Wang S, O'Brien KD, Marcovina SM, Wight TN, Vaisar T, de Beer MC, de Beer FC, Osborne WR, Elkon KB, Chait A -
Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice.
Arteriosclerosis, Thrombosis, and Vascular BiologyHu JH, Wei H, Jaffe M, Airhart N, Du L, Angelov SN, Yan J, Allen JK, Kang I, Wight TN, Fox K, Smith A, Enstrom R, Dichek DA -
Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis.
The Journal of Clinical InvestigationNagy N, Kaber G, Johnson PY, Gebe JA, Preisinger A, Falk BA, Sunkari VG, Gooden MD, Vernon RB, Bogdani M, Kuipers HF, Day AJ, Campbell DJ, Wight TN, Bollyky PL -
Expression of V3 Versican by Rat Arterial Smooth Muscle Cells Promotes Differentiated and Anti-inflammatory Phenotypes.
The Journal of Biological ChemistryKang I, Barth JL, Sproul EP, Yoon DW, Workman GA, Braun KR, Argraves WS, Wight TN -
Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study.
AtherosclerosisOtsuka F, Kramer MC, Woudstra P, Yahagi K, Ladich E, Finn AV, de Winter RJ, Kolodgie FD, Wight TN, Davis HR, Joner M, Virmani R -
Hyaluronan: A Mediator of Islet Dysfunction and Destruction in Diabetes?
The Journal of Histochemistry and CytochemistryHull RL, Bogdani M, Nagy N, Johnson PY, Wight TN -
Pivotal role for decorin in angiogenesis.
Matrix BiologyJärveläinen H, Sainio A, Wight TN -
4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.
Frontiers in ImmunologyNagy N, Kuipers HF, Frymoyer AR, Ishak HD, Bollyky JB, Wight TN, Bollyky PL -
Hyaluronan Controls the Deposition of Fibronectin and Collagen and Modulates TGF-β1 Induction of Lung Myofibroblasts.
Matrix BiologyEvanko SP, Potter-Perigo S, Petty LJ, Workman GA, Wight TN -
Hyaluronan in aged collagen matrix increases prostate epithelial cell proliferation.
In Vitro Cellular & Developmental Biology. AnimalDamodarasamy M, Vernon RB, Chan CK, Plymate SR, Wight TN, Reed MJ -
The detection of glycosaminoglycans in pancreatic islets and lymphoid tissues.
Methods in Molecular BiologyBogdani M, Simeonovic C, Nagy N, Johnson PY, Chan CK, Wight TN -
A role for versican in the development of leiomyosarcoma.
The Journal of Biological ChemistryKeire PA, Bressler SL, Lemire JM, Edris B, Rubin BP, Rahmani M, McManus BM, van de Rijn M, Wight TN -
Extracellular matrix components in the pathogenesis of type 1 diabetes.
Current Diabetes ReportsBogdani M, Korpos E, Simeonovic CJ, Parish CR, Sorokin L, Wight TN