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Versican is produced by Trif- and type I interferon-dependent signaling in macrophages and contributes to fine control of innate immunity in lungs.
American Journal of Physiology. Lung Cellular and Molecular PhysiologyChang MY, Kang I, Gale M Jr, Manicone AM, Kinsella MG, Braun KR, Wigmosta T, Parks WC, Altemeier WA, Wight TN, Frevert CW -
Crosstalk Between T Lymphocytes and Lung Fibroblasts: Generation of a Hyaluronan-Enriched Extracellular Matrix Adhesive for Monocytes.
Journal of Cellular BiochemistryGaucherand L, Falk BA, Evanko SP, Workman G, Chan CK, Wight TN -
Provisional matrix: A role for versican and hyaluronan.
Matrix BiologyWight TN -
Microvasculature of the Mouse Cerebral Cortex Exhibits Increased Accumulation and Synthesis of Hyaluronan With Aging.
The Journals of Gerontology. Series A, Biological Sciences and Medical SciencesReed MJ, Vernon RB, Damodarasamy M, Chan CK, Wight TN, Bentov I, Banks WA -
A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis.
The European Respiratory JournalDasgupta A, Kjarsgaard M, Capaldi D, Radford K, Aleman F, Boylan C, Altman LC, Wight TN, Parraga G, O'Byrne PM, Nair P -
Interleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling.
FASEB JournalBalaji S, Wang X, King A, Le LD, Bhattacharya SS, Moles CM, Butte MJ, de Jesus Perez VA, Liechty KW, Wight TN, Crombleholme TM, Bollyky PL, Keswani SG -
Interplay of extracellular matrix and leukocytes in lung inflammation.
Cellular ImmunologyWight TN, Frevert CW, Debley JS, Reeves SR, Parks WC, Ziegler SF -
Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation.
The Journal of Biological ChemistryKang I, Harten IA, Chang MY, Braun KR, Sheih A, Nivison MP, Johnson PY, Workman G, Kaber G, Evanko SP, Chan CK, Merrilees MJ, Ziegler SF, Kinsella MG, Frevert CW, Wight TN -
Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin.
Journal of Tissue Engineering and Regenerative MedicineMerrilees MJ, Falk BA, Zuo N, Dickinson ME, May BC, Wight TN -
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression.
Science Translational MedicineHundhausen C, Roth A, Whalen E, Chen J, Schneider A, Long SA, Wei S, Rawlings R, Kinsman M, Evanko SP, Wight TN, Greenbaum CJ, Cerosaletti K, Buckner JH -
Versican accumulates in vascular lesions in pulmonary arterial hypertension.
Pulmonary CirculationChang YT, Chan CK, Eriksson I, Johnson PY, Cao X, Westöö C, Norvik C, Andersson-Sjöland A, Westergren-Thorsson G, Johansson S, Hedin U, Kjellén L, Wight TN, Tran-Lundmark K -
The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice.
Clinical and Experimental ImmunologyKuipers HF, Nagy N, Ruppert SM, Sunkari VG, Marshall PL, Gebe JA, Ishak HD, Keswani SG, Bollyky J, Frymoyer AR, Wight TN, Steinman L, Bollyky PL -
G1 Domain of Versican Regulates Hyaluronan Organization and the Phenotype of Cultured Human Dermal Fibroblasts.
The Journal of Histochemistry and CytochemistryMerrilees MJ, Zuo N, Evanko SP, Day AJ, Wight TN -
Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma.
The Journal of Histochemistry and CytochemistryReeves SR, Kaber G, Sheih A, Cheng G, Aronica MA, Merrilees MJ, Debley JS, Frevert CW, Ziegler SF, Wight TN -
Surgical marking pen dye inhibits saphenous vein cell proliferation and migration in saphenous vein graft tissue.
Journal of Vascular SurgeryKikuchi S, Kenagy RD, Gao L, Wight TN, Azuma N, Sobel M, Clowes AW
