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Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection.
The Journal of Biological ChemistryKellar GG, Barrow KA, Rich LM, Debley JS, Wight TN, Ziegler SF, Reeves SR -
Modulation of hyaluronan synthases and involvement of T cell-derived hyaluronan in autoimmune responses to transplanted islets.
Matrix Biology PlusGebe JA, Gooden MD, Workman G, Nagy N, Bollyky PL, Wight TN, Vernon RB -
Juvenile, but Not Adult, Mice Display Increased Myeloid Recruitment and Extracellular Matrix Remodeling during Respiratory Syncytial Virus Infection.
Journal of ImmunologyKellar GG, Reeves SR, Barrow KA, Debley JS, Wight TN, Ziegler SF -
A Role for HAPLN1 During Phenotypic Modulation of Human Lung Fibroblasts In Vitro.
The Journal of Histochemistry and CytochemistryEvanko SP, Gooden MD, Kang I, Chan CK, Vernon RB, Wight TN -
Exuberant fibroblast activity compromises lung function via ADAMTS4.
NatureBoyd DF, Allen EK, Randolph AG, Guo XJ, Weng Y, Sanders CJ, Bajracharya R, Lee NK, Guy CS, Vogel P, Guan W, Li Y, Liu X, Novak T, Newhams MM, Fabrizio TP, Wohlgemuth N, Mourani PM, PALISI Pediatric Intensive Care Influenza (PICFLU) Investigators., Wight TN, Schultz-Cherry S, Cormier SA, Shaw-Saliba K, Pekosz A, Rothman RE, Chen KF, Yang Z, Webby RJ, Zhong N, Crawford JC, Thomas PG -
Hypothalamic perineuronal net assembly is required for sustained diabetes remission induced by fibroblast growth factor 1 in rats.
Nature MetabolismAlonge KM, Mirzadeh Z, Scarlett JM, Logsdon AF, Brown JM, Cabrales E, Chan CK, Kaiyala KJ, Bentsen MA, Banks WA, Guttman M, Wight TN, Morton GJ, Schwartz MW -
Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties.
JCI InsightHan CY, Kang I, Omer M, Wang S, Wietecha T, Wight TN, Chait A -
Inhibitory Effects of PRG4 on Migration and Proliferation of Human Venous Cells.
The Journal of Surgical ResearchWang L, Kikuchi S, Schmidt TA, Hoofnagle M, Wight TN, Azuma N, Tang GL, Sobel M, Velamoor GR, Mokadam NA, Kenagy RD -
The synthesis and secretion of versican isoform V3 by mammalian cells: A role for N-linked glycosylation.
Matrix BiologyHarten IA, Kaber G, Agarwal KJ, Kang I, Ibarrientos SR, Workman G, Chan CK, Nivison MP, Nagy N, Braun KR, Kinsella MG, Merrilees MJ, Wight TN -
Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity.
Cell ReportsHan CY, Kang I, Harten IA, Gebe JA, Chan CK, Omer M, Alonge KM, den Hartigh LJ, Gomes Kjerulf D, Goodspeed L, Subramanian S, Wang S, Kim F, Birk DE, Wight TN, Chait A -
High-molecular weight hyaluronan attenuates tubulointerstitial scarring in kidney injury.
JCI InsightWang X, Balaji S, Steen EH, Blum AJ, Li H, Chan CK, Manson SR, Lu TC, Rae MM, Austin PF, Wight TN, Bollyky PL, Cheng J, Keswani SG -
Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation.
Frontiers in ImmunologyWight TN, Kang I, Evanko SP, Harten IA, Chang MY, Pearce OMT, Allen CE, Frevert CW -
Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates.
DiabetologiaBogdani M, Speake C, Dufort MJ, Johnson PY, Larmore MJ, Day AJ, Wight TN, Lernmark A, Greenbaum CJ -
Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.
Frontiers in ImmunologyReeves SR, Barrow KA, Rich LM, White MP, Shubin NJ, Chan CK, Kang I, Ziegler SF, Piliponsky AM, Wight TN, Debley JS -
Targeting the Extracellular Matrix Promotes Healing Following Myocardial Infarction.
Circulation ResearchWight TN, Vernon RB
