-
Oct 2022
CBLB Deficiency in Human CD4+ T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.
J ImmunolSong J, Anderson W, Hu A, Obata-Ninomiya K, Ziegler SF, Rawlings DJ, Buckner JH -
May 2022
Emerging role for thymic stromal lymphopoietin-responsive regulatory T cells in colorectal cancer progression in humans and mice.
Sci Transl MedObata-Ninomiya K, de Jesus Carrion S, Hu A, Ziegler SF -
Aug 2019
Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology.
J Allergy Clin ImmunolTumes D, Hirahara K, Papadopoulos M, Shinoda K, Onodera A, Kumagai J, Yip KH, Pant H, Kokubo K, Kiuchi M, Aoki A, Obata-Ninomiya K, Tokoyoda K, Endo Y, Kimura MY, Nakayama T -
Feb 2019
ACC1 determines memory potential of individual CD4(+) T cells by regulating de novo fatty acid biosynthesis.
Nat MetabEndo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ, Nakayama T -
Oct 2018
CXCR6(+)ST2(+) memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth.
Proc Natl Acad Sci U S AObata-Ninomiya K, Ishiwata K, Nakano H, Endo Y, Ichikawa T, Onodera A, Hirahara K, Okamoto Y, Kanuka H, Nakayama T -
Feb 2018
IL-33/ST2 contributes to severe symptoms in Plasmodium chabaudi-infected BALB/c mice.
Parasitol Int.Seki T, Obata-Ninomiya K, Shimogawara-Furushima R, Arai T, Akao N, Hoshino T, Ohta N -
Feb 2015
The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.
ImmunityEndo Y, Hirahara K, Linuma T, Shinoda K, Tumes DJ, Asou HK, Matsugae N, Obata-Ninomiya K, Yamamoto H, Motohashi S, Oboki K, Nakae S, Saito H, Okamoto Y, Nakayama T -
Feb 2015
The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.
ImmunityTsai SH, Kinoshita M, Kusu T, Kayama H, Okumura R, Ikeda K, Shimada Y, Takeda A, Yoshikawa S, Obata-Ninomiya K, Kurashima Y, Sato S, Umemoto E, Kiyono H, Karasuyama H, Takeda K -
Sep 2014
Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Proc Natl Acad Sci U S AWatanabe Y, Onodera A, Kanai U, Ichikawa T, Obata-Ninomiya K, Wada T, Kiuchi M, Iwamura C, Tumes DJ, Shinoda K, Yagi R, Motohashi S, Hirahara K, Nakayama T -
May 2014
NADPH oxidase-independent formation of extracellular DNA traps by basophils.
J ImmunolMorshed M, Hlushchuk R, Simon D, Walls AF, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon HU, Yousefi S -
Dec 2013
Basophil depletion downregulates Schistosoma mansoni egg-induced granuloma formation.
Parasitol Int.Anyan WK, Seki T, Kumagai T, Obata-Ninomiya K, Furushima-Shimogawara R, Kwansa-Bentum B, Akao N, Bosompem KM, Boakye DA, Wilson MD, Karasuyama H, Ohta N -
Nov 2013
The skin is an important bulwark of acquired immunity against intestinal helminths.
J Exp MedObata-Ninomiya K, Ishiwata K, Tsutsui H, Nei Y, Yoshikawa S, Kawano Y, Minegishi Y, Ohta N, Watanabe N, Kanuka H, Karasuyama H -
Nov 2013
GATA-1 regulates the generation and function of basophils.
Proc Natl Acad Sci U S ANei Y, Obata-Ninomiya K, Tsutsui H, Ishiwata K, Miyasaka M, Matsumoto K, Nakae S, Kanuka H, Inase N, Karasuyama H -
Jul 2013
Thymic stromal lymphopoietin-elicited basophil responses promote eosinophilic esophagitis.
Nat MedNoti M, Wojno ED, Kim BS, Siracusa MC, Giacomin PR, Nair MG, Benitez AJ, Ruymann KR, Muir AB, Hill DA, Chikwava KR, Moghaddam AE, Sattentau QJ, Alex A, Zhou C, Yearley JH, Menard-Katcher P, Kubo M, Obata-Ninomiya K, Karasuyama H, Comeau MR, Brown-Whitehorn T, de Waal Malefyt R, Sleiman PM, Hakonarson H, Cianferoni A, Falk GW, Wang ML, Spergel JM, Artis D -
Jun 2012
Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction.
J Dermatol SciJin G, Matsushita T, Hamaguchi Y, Le Huu D, Ishii T, Hasegawa M, Obata K, Karasuyama H, Takehara K, Fujimoto M
