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Oct 2024
Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
CellsNagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL -
Aug 2024
Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review.
AtherosclerosisKumarapperuma H, Chia ZJ, Malapitan SM, Wight TN, Little PJ, Kamato D -
Mar 2024
Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate.
Cancer Res CommunHirani P, McDermott J, Rajeeve V, Cutillas PR, Jones JL, Pennington DJ, Wight TN, Santamaria S, Alonge KM, Pearce OMT -
Feb 2024
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Nat CommunMartinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF -
Sep 2023
Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes.
Matrix BiolNagy N, Kaber G, Sunkari VG, Marshall PL, Hargil A, Kuipers HF, Ishak HD, Bogdani M, Hull RL, Grandoch M, Fischer JW, McLaughlin TL, Wight TN, Bollyky PL -
Jul 2023
Commentary on a Classic JHC Article on Intracellular Hyaluronan Associated with the Mitotic Spindle.
J Histochem CytochemEvanko SP, Wight TN -
Jul 2023
V3: An Enigmatic Isoform of the Proteoglycan Versican.
Am J Physiol Cell PhysiolWight TN, Day AJ, Kang I, Harten IA, Kaber G, Briggs DC, Braun KR, Lemire JM, Kinsella MG, Hinek A, Merrilees MJ -
Feb 2023
FOXP3(+) regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues.
bioRxivMartinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF -
Jun 2022
Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections.
JCI InsightKratochvil MJ, Kaber G, Demirdjian S, Cai PC, Burgener EB, Nagy N, Barlow GL, Popescu M, Nicolls MR, Ozawa MG, Regula DP, Pacheco-Navarro AE, Yang S, de Jesus Perez VA, Karmouty-Quintana H, Peters AM, Zhao B, Buja ML, Johnson PY, Vernon RB, Wight TN, Stanford COVID-19 Biobank Study Group., Milla CE, Rogers AJ, Spakowitz AJ, Heilshorn SC, Bollyky PL -
May 2022
Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination.
Nat CommunGhorbani S, Jelinek E, Jain R, Buehner B, Li C, Lozinski BM, Sarkar S, Kaushik DK, Dong Y, Wight TN, Karimi-Abdolrezaee S, Schenk GJ, Strijbis EM, Geurts J, Zhang P, Ling CC, Yong VW -
Apr 2022
Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro.
Matrix Biol PlusKang I, Hundhausen C, Evanko SP, Malapati P, Workman G, Chan CK, Rims C, Firestein GS, Boyle DL, MacDonald KM, Buckner JH, Wight TN -
Jan 2022
Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues.
Methods Mol BiolBogdani M, Simeonovic C, Nagy N, Johnson PY, Chan CK, Wight TN -
Aug 2021
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
Front OncolHirani P, Gauthier V, Allen CE, Wight TN, Pearce OMT -
Jun 2021
Autocrine Hyaluronan Influences Sprouting and Lumen Formation During HUVEC Tubulogenesis In Vitro.
J Histochem CytochemVernon RB, Gooden MD, Chan CK, Workman G, Obika M, Wight TN -
Mar 2021
The extracellular matrix molecules versican and hyaluronan in urethral and vaginal tissues in stress urinary incontinence.
Neurourol UrodynHarten IA, Evanko SP, Choe CH, Lee EW, Patel BN, Bogdani M, Wight TN, Lee UJ