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Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
CellsNagy N, Czepiel KS, Kaber G, Stefanovski D, Hargil A, Pennetzdorfer N, Targ R, Reghupaty SC, Wight TN, Vernon RB, Hull-Meichle RL, Marshall P, Medina CO, Martinez H, Kalinowski A, Paladini RD, Garantziotis S, Knowles JW, Bollyky PL -
Response to retention hypothesis as a source of targets for arterial wall-directed therapies to prevent atherosclerosis: A critical review.
AtherosclerosisKumarapperuma H, Chia ZJ, Malapitan SM, Wight TN, Little PJ, Kamato D -
Versican associates with tumour immune phenotype and limits T cell trafficking via chondroitin sulfate.
Cancer Research CommunicationsHirani P, McDermott J, Rajeeve V, Cutillas PR, Jones JL, Pennington DJ, Wight TN, Santamaria S, Alonge KM, Pearce OMT -
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue.
Nature CommunicationsMartinez HA, Koliesnik I, Kaber G, Reid JK, Nagy N, Barlow G, Falk BA, Medina CO, Hargil A, Zihsler S, Vlodavsky I, Li JP, Pérez-Cruz M, Tang SW, Meyer EH, Wrenshall LE, Lord JD, Garcia KC, Palmer TD, Steinman L, Nepom GT, Wight TN, Bollyky PL, Kuipers HF -
Inhibition of hyaluronan synthesis prevents β-cell loss in obesity-associated type 2 diabetes.
Matrix BiologyNagy N, Kaber G, Sunkari VG, Marshall PL, Hargil A, Kuipers HF, Ishak HD, Bogdani M, Hull RL, Grandoch M, Fischer JW, McLaughlin TL, Wight TN, Bollyky PL -
Commentary on a Classic JHC Article on Intracellular Hyaluronan Associated with the Mitotic Spindle.
The Journal of Histochemistry and CytochemistryEvanko SP, Wight TN -
V3: An Enigmatic Isoform of the Proteoglycan Versican.
American Journal of Physiology. Cell PhysiologyWight TN, Day AJ, Kang I, Harten IA, Kaber G, Briggs DC, Braun KR, Lemire JM, Kinsella MG, Hinek A, Merrilees MJ -
Biochemical, biophysical, and immunological characterization of respiratory secretions in severe SARS-CoV-2 infections.
JCI InsightKratochvil MJ, Kaber G, Demirdjian S, Cai PC, Burgener EB, Nagy N, Barlow GL, Popescu M, Nicolls MR, Ozawa MG, Regula DP, Pacheco-Navarro AE, Yang S, de Jesus Perez VA, Karmouty-Quintana H, Peters AM, Zhao B, Buja ML, Johnson PY, Vernon RB, Wight TN, Stanford COVID-19 Biobank Study Group., Milla CE, Rogers AJ, Spakowitz AJ, Heilshorn SC, Bollyky PL -
Versican promotes T helper 17 cytotoxic inflammation and impedes oligodendrocyte precursor cell remyelination.
Nature CommunicationsGhorbani S, Jelinek E, Jain R, Buehner B, Li C, Lozinski BM, Sarkar S, Kaushik DK, Dong Y, Wight TN, Karimi-Abdolrezaee S, Schenk GJ, Strijbis EM, Geurts J, Zhang P, Ling CC, Yong VW -
Crosstalk between CD4 T cells and synovial fibroblasts from human arthritic joints promotes hyaluronan-dependent leukocyte adhesion and inflammatory cytokine expression in vitro.
Matrix Biology PlusKang I, Hundhausen C, Evanko SP, Malapati P, Workman G, Chan CK, Rims C, Firestein GS, Boyle DL, MacDonald KM, Buckner JH, Wight TN -
Detection of Glycosaminoglycans in Pancreatic Islets and Lymphoid Tissues.
Methods in Molecular BiologyBogdani M, Simeonovic C, Nagy N, Johnson PY, Chan CK, Wight TN -
Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer.
Frontiers in OncologyHirani P, Gauthier V, Allen CE, Wight TN, Pearce OMT -
Autocrine Hyaluronan Influences Sprouting and Lumen Formation During HUVEC Tubulogenesis In Vitro.
The Journal of Histochemistry and CytochemistryVernon RB, Gooden MD, Chan CK, Workman G, Obika M, Wight TN -
The extracellular matrix molecules versican and hyaluronan in urethral and vaginal tissues in stress urinary incontinence.
Neurourology and UrodynamicsHarten IA, Evanko SP, Choe CH, Lee EW, Patel BN, Bogdani M, Wight TN, Lee UJ -
Hyaluronan synthesis inhibition impairs antigen presentation and delays transplantation rejection.
Matrix BiologyMarshall PL, Nagy N, Kaber G, Barlow GL, Ramesh A, Xie BJ, Linde MH, Haddock NL, Lester CA, Tran QL, de Vries CR, Hargil A, Malkovskiy AV, Gurevich I, Martinez HA, Kuipers HF, Yadava K, Zhang X, Evanko SP, Gebe JA, Wang X, Vernon RB, de la Motte C, Wight TN, Engleman EG, Krams SM, Meyer EH, Bollyky PL