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Short-term IL-1beta blockade reduces monocyte CD11b integrin expression in an IL-8 dependent fashion in patients with type 1 diabetes.
Clinical ImmunologySanda S, Bollyky J, Standifer N, Nepom GT, Hamerman JA, Greenbaum CJ -
Prediction and pathogenesis in type 1 diabetes.
ImmunityZiegler AG, Nepom GT -
Biobanking, consent, and commercialization in international genetics research: the Type 1 Diabetes Genetics Consortium.
Clinical TrialsHall MA, King NM, Perdue LH, Hilner JE, Akolkar B, Greenbaum CJ, McKeon C, T1DGC. -
Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb Teplizumab preserves insulin production for up to 5 years.
Clinical ImmunologyHerold KC, Gitelman S, Greenbaum CJ, Puck J, Hagopian WA, Gottlieb PA, Sayre PH, Bianchine PJ, Wong E, Seyfert-Margolis V, Bourcier K, Bluestone JA, Immune Tolerance Network ITN007AI Study Group. -
Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects.
European Journal of ImmunologyLong SA, Walker MR, Rieck M, James EA, Kwok WW, Sanda S, Pihoker C, Nepom GT, Buckner JH -
Type 1 Diabetes TrialNet--an international collaborative clinical trials network.
Annals of the New York Academy of SciencesSkyler JS, Greenbaum CJ, Lachin JM, Leschek E, Rafkin-Mervis L, Savage P, Spain L, Type 1 Diabetes TrialNet Study Group. -
Low-affinity major histocompatibility complex-binding peptides in type 1 diabetes.
DiabetesJames EA, Kwok WW -
Role of insulin resistance in predicting progression to type 1 diabetes.
Diabetes CareXu P, Cuthbertson D, Greenbaum CJ, Palmer JP, Krischer JP, Diabetes Prevention Trial Type 1 Study Group. -
Adipocyte-derived serum amyloid A3 and hyaluronan play a role in monocyte recruitment and adhesion.
DiabetesHan CY, Subramanian S, Chan CK, Omer M, Chiba T, Wight TN, Chait A -
Editorial: The role of glucagon in postprandial hyperglycemia--the jury's still out.
The Journal of Clinical Endocrinology and MetabolismBollyky J, Greenbaum CJ -
Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes.
The Journal of Clinical Endocrinology and MetabolismRedondo MJ, Babu S, Zeidler A, Orban T, Yu L, Greenbaum CJ, Palmer JP, Cuthbertson DD, Eisenbarth GS, Krischer JP, Schatz DA, Diabetes Prevention Trial Type 1 Study Group. -
Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo.
Journal of ImmunologyWeber SE, Harbertson J, Godebu E, Mros GA, Padrick RC, Carson BD, Ziegler SF, Bradley LM -
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.
Journal of ImmunologyYang J, Danke NA, Berger D, Reichstetter S, Reijonen H, Greenbaum CJ, Pihoker C, James EA, Kwok WW -
Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes.
American Journal of TherapeuticsMallone R, Nepom GT -
Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.
Diabetes CareSkyler JS, Krischer JP, Wolfsdorf J, Cowie C, Palmer JP, Greenbaum CJ, Cuthbertson DD, Rafkin-Mervis LE, Chase HP, Leschek E