Biorepository: Neurologic Diseases

Multiple Sclerosis

What is the neurologic diseases biorepository?

The Multiple Sclerosis - Neurological Diseases Biorepository is a confidential list of people with multiple sclerosis (MS) and other neurological diseases who are willing to donate samples and provide health information for scientific research.

Scientists use this information to understand how and why MS and other neurologic diseases happen, and make progress toward better treatments and prevention. All of the information gathered is kept confidential, and samples and health information are coded with numbers, not names.

We are also looking for family members of all ages who do not have a neurologic disease other immune-mediated or autoimmune diseases, to join our Healthy Control Biorepository.

Participating in research typically involves a 45- minute to -one- hour visit to BRI in downtown Seattle. Our team will collect a blood sample and ask questions about your personal and family medical history. All samples and information are kept confidential. Learn more: Biorepository FAQ

Learn more about multiple sclerosis. 

Participate in Neurologic Disease Research

We are currently enrolling individuals, age 18 and older, with a diagnosis of multiple sclerosis who are and are not receiving immune-modulating treatment.

Are you living with a neurological disease?

Consider donating to our biorepository to help advance research.
Donate to our Biorepository
Mariko Kita
Affiliate Investigator

Mariko Kita, MD

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What Neurologic Disease Research is BRI Conducting?

  • Understanding how and why MS starts
  • Seeking out new targets that could lead to new ways to treat or prevent MS and other neurologic diseases
  • Identifying more personalized medicines for MS and other neurologic diseases

Learn more about multiple sclerosis research studies.

Labs Studying Neurological Diseases

Bettelli Lab Main

Bettelli Lab

The main focus of the Bettelli Lab is to identify the cell types of the immune system and mechanisms, which induce and regulate the development of autoimmunity.
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Buckner Lab Main

Buckner Lab

The Buckner Lab is focused on identifying the underlying mechanisms by which regulation of the adaptive immune response fails or is overcome in the setting of human autoimmunity. 
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Campbell Lab Main

Campbell Lab

The Campbell laboratory is interested in understanding the basis for T cell activation, function and tolerance.
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Kwok Research Project Main - DNA-barcoded HLA class II tetramers

Kwok Lab

The Kwok lab uses tetramers and other antigen specific T cell assays to examine autoreactive T cells in  autoimmune diseases in order to provide insights into disease mechanisms and identify strategies for disease intervention.
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Speake Research Project Main - TrialNet Pathway to Prevention

Speake Lab

The Speake group is interested in advancing clinical research – especially in type 1 diabetes, but also in the context of other immune-mediated diseases.
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Stefani Lab Main

Stefani Lab

The goal of our research is to better understand mechanisms of sensing and repair during diseases like cancer, infections, and neurodegenerative disorders.
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Blog Stories

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June 30, 2023

What Do T Cells Like to Eat? The Answer Could Stop Multiple Sclerosis

Cells, like people, get their energy from sugars, proteins and fats. Many cells have highly specialized diets — think of some loving kale while others prefer Texas BBQ.
Read Article
Dr. Buckner reviewing information
February 4, 2023

BRI's Vision of Immune Health

A message from BRI President Jane Buckner, MD, about BRI's new, broader vision for immune health.
Read Article
Blog Main Image - Scientific Collagen Fibers Skin
December 14, 2022

Using AI and VR to Advance Research

Caroline Stefani, PhD, became fascinated with the immune system while pursuing her doctorate in microbiology. She loved using imaging tools to examine the worlds of cells and bacteria. But one thing frustrated her. 

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