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Mar 2025
From the bench to the clinic: basophils and type 2 epithelial cytokines of thymic stromal lymphopoietin and IL-33.
Clin Transl ImmunologyObata-Ninomiya K, Jayaraman T, Ziegler SF -
May 2024
SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
J ImmunolChiu H, Weinstein KN, Spath S, Hu A, Varela S, Obata-Ninomiya K, Ziegler SF -
Mar 2023
Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis.
J Exp MedSo L, Obata-Ninomiya K, Hu A, Muir VS, Takamori A, Song J, Buckner JH, Savan R, Ziegler SF -
Oct 2022
CBLB Deficiency in Human CD4+ T Cells Results in Resistance to T Regulatory Suppression through Multiple Mechanisms.
J ImmunolSong J, Anderson W, Hu A, Obata-Ninomiya K, Ziegler SF, Rawlings DJ, Buckner JH -
May 2022
Emerging role for thymic stromal lymphopoietin-responsive regulatory T cells in colorectal cancer progression in humans and mice.
Sci Transl MedObata-Ninomiya K, de Jesus Carrion S, Hu A, Ziegler SF -
Nov 2020
Basophils and Eosinophils in Nematode Infections.
Front ImmunolObata-Ninomiya K, Domeier PP, Ziegler SF -
Aug 2019
Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology.
J Allergy Clin ImmunolTumes D, Hirahara K, Papadopoulos M, Shinoda K, Onodera A, Kumagai J, Yip KH, Pant H, Kokubo K, Kiuchi M, Aoki A, Obata-Ninomiya K, Tokoyoda K, Endo Y, Kimura MY, Nakayama T -
Apr 2019
Epithelial cell-derived cytokines: more than just signaling the alarm.
J Clin InvestRoan F, Obata-Ninomiya K, Ziegler SF -
Feb 2019
ACC1 determines memory potential of individual CD4(+) T cells by regulating de novo fatty acid biosynthesis.
Nat MetabEndo Y, Onodera A, Obata-Ninomiya K, Koyama-Nasu R, Asou HK, Ito T, Yamamoto T, Kanno T, Nakajima T, Ishiwata K, Kanuka H, Tumes DJ, Nakayama T -
Oct 2018
CXCR6(+)ST2(+) memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth.
Proc Natl Acad Sci U S AObata-Ninomiya K, Ishiwata K, Nakano H, Endo Y, Ichikawa T, Onodera A, Hirahara K, Okamoto Y, Kanuka H, Nakayama T -
Feb 2018
IL-33/ST2 contributes to severe symptoms in Plasmodium chabaudi-infected BALB/c mice.
Parasitol Int.Seki T, Obata-Ninomiya K, Shimogawara-Furushima R, Arai T, Akao N, Hoshino T, Ohta N -
Feb 2015
The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.
ImmunityEndo Y, Hirahara K, Linuma T, Shinoda K, Tumes DJ, Asou HK, Matsugae N, Obata-Ninomiya K, Yamamoto H, Motohashi S, Oboki K, Nakae S, Saito H, Okamoto Y, Nakayama T -
Feb 2015
The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.
ImmunityTsai SH, Kinoshita M, Kusu T, Kayama H, Okumura R, Ikeda K, Shimada Y, Takeda A, Yoshikawa S, Obata-Ninomiya K, Kurashima Y, Sato S, Umemoto E, Kiyono H, Karasuyama H, Takeda K -
Sep 2014
Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Proc Natl Acad Sci U S AWatanabe Y, Onodera A, Kanai U, Ichikawa T, Obata-Ninomiya K, Wada T, Kiuchi M, Iwamura C, Tumes DJ, Shinoda K, Yagi R, Motohashi S, Hirahara K, Nakayama T -
May 2014
NADPH oxidase-independent formation of extracellular DNA traps by basophils.
J ImmunolMorshed M, Hlushchuk R, Simon D, Walls AF, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon HU, Yousefi S
