Introduction
The Morawski lab studies the adaptive immune response occurring during human inflammatory and autoimmune diseases of the skin and other barrier tissues.
Our approach integrates cellular and molecular techniques including in situ imaging, organotypic culture, and gene editing to understand how T cells reprogram the structural cells of the skin and in turn how signals from the tissue shape the immune repertoire.
We are especially interested in dissecting the immune-stromal networks that maintain homeostasis in the skin and those that are dysregulated during heterogeneous systemic diseases such as scleroderma and lupus.
Research Assistant Member
Peter Morawski, PhD
Principal Investigator, Morawski Lab; Center for Fundamental Immunology
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Featured Publications
Aug 2024
T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells.
bioRxiv
DeBerg HA, Fahning ML, Schlenker JD, Schmitt WP, Gratz IK, Carlin JS, Campbell DJ, Morawski PA
Mar 2022
Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity.
Cell
Rodda LB, Morawski PA, Pruner KB, Fahning ML, Howard CA, Franko N, Logue J, Eggenberger J, Stokes C, Golez I, Hale M, Gale M Jr, Chu HY, Campbell DJ, Pepper M
Sep 2021
High-throughput single-cell quantification of hundreds of proteins using conventional flow cytometry and machine learning.
Sci Adv
Becht E, Tolstrup D, Dutertre CA, Morawski PA, Campbell DJ, Ginhoux F, Newell EW, Gottardo R, Headley MB
Apr 2021
Designed proteins assemble antibodies into modular nanocages.
Science
Divine R, Dang HV, Ueda G, Fallas JA, Vulovic I, Sheffler W, Saini S, Zhao YT, Raj IX, Morawski PA, Jennewein MF, Homad LJ, Wan YH, Tooley MR, Seeger F, Etemadi A, Fahning ML, Lazarovits J, Roederer A, Walls AC, Stewart L, Mazloomi M, King NP, Campbell DJ, McGuire AT, Stamatatos L, Ruohola-Baker H, Mathieu J, Veesler D, Baker D
Jan 2021
Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.
Cell
Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M